Oscar er filmbranchens vigtigste pris. Den er blevet uddelt af det amerikanske filmakademi siden 1929. Prisen uddeles inden for en række forskellige kategorier, både kunstneriske og tekniske. Oscar-prisen for bedste mandlige hovedrolle gives til en skuespiller for en 'enestående præstation' (outstanding performance) i en hovedrolle. Der kan være op til fem nominerede skuespillere til prisen.
Prisen til årets vinder overrækkes almindeligvis af forrige års modtager.
Oscarpriserne uddeles som regel en søndag i februar eller marts, og årstallet nedenfor angiver det år, hvor prisen blev uddelt.
| År | Vinder | Film |
| 2024 | Cillian Murphy | Oppenheimer |
| 2023 | Brendan Fraser | The Whale |
| 2022 | Will Smith | King Richard |
| 2021 | Anthony Hopkins | The Father |
| 2020 | Joaquin Phoenix | Joker |
| 2019 | Rami Malek | Bohemian Rhapsody |
| 2018 | Gary Oldman | Darkest Hour |
| 2017 | Casey Affleck | Manchester by the Sea |
| 2016 | Leonardo DiCaprio | The Revenant |
| 2015 | Eddie Redmayne | The Theory of Everything |
| 2014 | Matthew McConaughey | Dallas Buyers Club |
| 2013 | Daniel Day-Lewis | Lincoln |
| 2012 | Jean Dujardin | The Artist |
| 2011 | Colin Firth | The King's Speech |
| 2010 | Jeff Bridges | Crazy Heart |
| 2009 | Sean Penn | Milk |
| 2008 | Daniel Day-Lewis | There Will Be Blood |
| 2007 | Forest Whitaker | The Last King of Scotland |
| 2006 | Philip Seymour Hoffman | Capote |
| 2005 | Jamie Foxx | Ray |
| 2004 | Sean Penn | Mystic River |
| 2003 | Adrien Brody | The Pianist |
| 2002 | Denzel Washington | Training Day |
| 2001 | Russell Crowe | Gladiator |
| 2000 | Kevin Spacey | American Beauty |
| 1999 | Roberto Benigni | Life Is Beautiful |
| 1998 | Jack Nicholson | As Good as It Gets |
| 1997 | Geoffrey Rush | Shine |
| 1996 | Nicolas Cage | Leaving Las Vegas |
| 1995 | Tom Hanks | Forrest Gump |
| 1994 | Tom Hanks | Philadelphia |
| 1993 | Al Pacino | Scent of a Woman |
| 1992 | Anthony Hopkins | The Silence of the Lambs |
| 1991 | Jeremy Irons | Reversal of Fortune |
| 1990 | Daniel Day Lewis | My Left Foot |
| 1989 | Dustin Hoffman | Rain Man |
| 1988 | Michael Douglas | Wall Street |
| 1987 | Paul Newman | The Color of Money |
| 1986 | William Hurt | Kiss of the Spider Woman |
| 1985 | F. Murray Abraham | Amadeus |
| 1984 | Robert Duvall | Tender Mercies |
| 1983 | Ben Kingsley | Gandhi |
| 1982 | Henry Fonda | On Golden Pond |
| 1981 | Robert De Niro | Raging Bull |
| 1980 | Dustin Hoffman | Kramer vs. Kramer |
| 1979 | Jon Voight | Coming Home |
| 1978 | Richard Dreyfuss | The Goodbye Girl |
| 1977 | Peter Finch | Network |
| 1976 | Jack Nicholson | One Flew over the Cuckoo's Nest |
| 1975 | Art Carney | Harry and Tonto |
| 1974 | Jack Lemmon | Save the Tiger |
| 1973 | Marlon Brando | The Godfather |
| 1972 | Gene Hackman | The French Connection |
| 1971 | George C. Scott | Patton |
| 1970 | John Wayne | True Grit |
| 1969 | Cliff Robertson | Charly |
| 1968 | Rod Steiger | In the Heat of the Night |
| 1967 | Paul Scofield | A Man for All Seasons |
| 1966 | Lee Marvin | Cat Ballou |
| 1965 | Rex Harrison | My Fair Lady |
| 1964 | Sidney Poitier | Lilies of the Field |
| 1963 | Gregory Peck | To Kill a Mockingbird |
| 1962 | Maximilian Schell | Judgment at Nuremberg |
| 1961 | Burt Lancaster | Elmer Gantry |
| 1960 | Charlton Heston | Ben-Hur |
| 1959 | David Niven | Separate Tables |
| 1958 | Alec Guinness | The Bridge on the River Kwai |
| 1957 | Yul Brynner | The King and I |
| 1956 | Ernest Borgnine | Marty |
| 1955 | Marlon Brando | On the Waterfront |
| 1954 | William Holden | Stalag 17 |
| 1953 | Gary Cooper | High Noon |
| 1952 | Humphrey Bogart | The African Queen |
| 1951 | José Ferrer | Cyrano de Bergerac |
| 1950 | Broderick Crawford | All the King's Men |
| 1949 | Laurence Olivier | Hamlet |
| 1948 | Ronald Colman | A Double Life |
| 1947 | Fredric March | The Best Years of Our Lives |
| 1946 | Ray Milland | The Lost Weekend |
| 1945 | Bing Crosby | Going My Way |
| 1944 | Paul Lukas | Watch on the Rhine |
| 1943 | James Cagney | Yankee Doodle Dandy |
| 1942 | Gary Cooper | Sergeant York |
| 1941 | James Stewart | The Philadelphia Story |
| 1940 | Robert Donat | Goodbye, Mr. Chips |
| 1939 | Spencer Tracy | Boys Town |
| 1938 | Spencer Tracy | Captains Courageous |
| 1937 | Paul Muni | The Story of Louis Pasteur |
| 1936 | Victor McLaglen | The Informer |
| 1935 | Clark Gable | It Happened One Night |
| 1934 | Charles Laughton | The Private Life of Henry VIII |
| 1933 | Wallace Beery | The Champ |
| 1932 | Lionel Barrymore | A Free Soul |
| 1931 | George Arliss | Disraeli |
| 1930 | Warner Baxter | In Old Arizona |
| 1929 | Emil Jannings | The Last Command |
Ni skuespillere har vundet prisen som bedste mandlige hovedrolle to gange.
| Vinder | År |
| Anthony Hopkins | 1992, 2021 |
| Daniel Day-Lewis | 2008, 2013 |
| Sean Penn | 2004, 2009 |
| Jack Nicholson | 1976, 1998 |
| Tom Hanks | 1994, 1995 |
| Dustin Hoffman | 1980, 1989 |
| Marlon Brando | 1955, 1973 |
| Gary Cooper | 1942, 1953 |
| Spencer Tracy | 1938, 1939 |
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